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    • 兔抗RNF20多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW20474
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:兔抗RNF20多克隆抗體

    英文名稱 Anti-RNF20 rabbit polyclonal antibody

    別      名: BRE1; BRE1A; hBRE1

    相關(guān)類別: 一抗

    儲(chǔ)      存: 冷凍(-20℃)

    宿      主: Rabbit

    抗      原: RNF20

    反應(yīng)種屬: Human, Mouse

    標(biāo)記物: Unconjugate

    克隆類型 rabbit polyclonal


    技術(shù)規(guī)格

    Background:

    The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    RNF20

    Immunogen:

    Fusion protein of human RNF20

    Full name:

    ring finger protein 20, E3 ubiquitin protein ligase

    Synonyms:

    BRE1; BRE1A; hBRE1

    SwissProt:

    Q5VTR2

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human esophagus cancer and human colon cancer

    IHC Recommend dilution:

    10-50

    WB Predicted band size:

    114 kDa

    WB Positive control:

    Hela, Jurkat, 231, A375, A172 and Lovo cells

    WB Recommended dilution:

    500-2000






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