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    • 兔抗PTPRK多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW19427
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:兔抗PTPRK多克隆抗體 

    英文名稱: Anti-PTPRK rabbit polyclonal antibody

    別      名: R-PTP-kappa

    抗      原: PTPRK

    儲      存: 冷凍(-20℃)

    宿      主: Rabbit

    相關(guān)類別: 一抗

    反應(yīng)種屬: Human

    標(biāo)記物: Unconjugate

    克隆類型: rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.

    Applications:

    ELISA, IHC

    Name of antibody:

    PTPRK

    Immunogen:

    Fusion protein of human PTPRK

    Full name:

    protein tyrosine phosphatase, receptor type, K

    Synonyms:

    R-PTP-kappa

    SwissProt:

    Q6P493

    ELISA Recommended dilution:

    1000-5000

    IHC positive control:

    Human liver cancer and Human ovarian cancer

    IHC Recommend dilution:

    25-100



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