購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗ATF4(Ab-219) 多克隆抗體
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Background: |
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production By similarity. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. |
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Applications: |
WB |
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Name of antibody: |
ATF4(Ab-219) |
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Immunogen: |
Synthesized peptide derived from C-terminal of human ATF4. |
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Full name: |
activating transcription factor 4 |
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Synonyms： |
CREB2; TXREB; CREB-2; TAXREB67 |
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SwissProt: |
P18848 |
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WB Predicted band size: |
39 kDa |
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WB Positive control: |
A549 cells and Jurkat cells lysates |
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WB Recommended dilution: |
500-3000 |
