購物車
幫助
021-54845833/15800441009
|
Background: |
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
ELAC2 |
|
Immunogen: |
Fusion protein of human ELAC2 |
|
Full name: |
elaC ribonuclease Z 2 |
|
Synonyms: |
ELC2; HPC2; COXPD17 |
|
SwissProt: |
Q9BQ52 |
|
IHC positive control: |
Human gastric cancer and human liver cancer |
|
IHC Recommend dilution: |
50-200 |
|
WB Predicted band size: |
92 kDa |
|
WB Positive control: |
LoVo and Hela cells |
|
WB Recommended dilution: |
200-1000 |
