購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EDA2R |
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Immunogen: |
Fusion protein of human EDA2R |
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Full name: |
ectodysplasin A2 receptor |
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Synonyms： |
XEDAR; EDAA2R; EDA-A2R; TNFRSF27 |
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SwissProt: |
Q9HAV5 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer and human ovarian cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
33 kDa |
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WB Positive control: |
293T cells |
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WB Recommended dilution: |
500-2000 |
