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021-54845833/15800441009
英文名稱： HLA-E Antigen (Recombinant Protein)
別 名： QA1; HLA-6.2
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
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Fusion protein corresponding to a region derived from 22-221 amino acids of human HLA-E |
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Full name: |
major histocompatibility complex, class I, E |
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Synonyms: |
QA1; HLA-6.2 |
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Swissprot: |
P13747 |
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Gene Accession: |
BC002578 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
