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中文名稱： 兔抗MCM3多克隆抗體
英文名稱： Anti-MCM3 rabbit polyclonal antibody
別 名： HCC5, P1.h, RLFB, P1-MCM3
抗 原： MCM3
儲 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MCM3 |
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Immunogen: |
Fusion protein of human MCM3 |
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Full name: |
minichromosome maintenance complex component 3 |
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Synonyms： |
HCC5, P1.h, RLFB, P1-MCM3 |
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SwissProt: |
P25205 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
91 kDa |
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WB Positive control: |
K562, Jurkat, hela and 293T cells |
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WB Recommended dilution: |
500-2000 |
