購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： ITGA2B 抗原（重組蛋白）
英文名稱： ITGA2B Antigen (Recombinant Protein)
別 名： integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; B
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 630-887 amino acids of human ITGA2B |
技術(shù)規(guī)格
|
Full name: |
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
|
Synonyms: |
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16 |
|
Swissprot: |
P08514 |
|
Gene Accession: |
BC117443 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
