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    • NECTIN4抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW17736
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ug
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    中文名稱: NECTIN4抗原(重組蛋白)

    英文名稱: NECTIN4 Antigen (Recombinant Protein)

    別       名: nectin cell adhesion molecule 4; LNIR; PRR4; EDSS1; PVRL4; nectin-4

    儲(chǔ)       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 371-510 amino acids of human NECTIN4

    技術(shù)規(guī)格

    Full name:

    nectin cell adhesion molecule 4

    Synonyms:

    LNIR; PRR4; EDSS1; PVRL4; nectin-4

    Swissprot:

    Q96NY8

    Gene Accession:

    BC010423

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

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