購物車
幫助
021-54845833/15800441009
中文名稱：ICAM1抗原（重組蛋白）
英文名稱： ICAM1 Antigen (Recombinant Protein)
別 名： BB2; CD54; P3.58
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 28-328 amino acids of human ICAM1 |
|
Full name: |
intercellular adhesion molecule 1 |
|
Synonyms: |
BB2; CD54; P3.58 |
|
Swissprot: |
P05362 |
|
Gene Accession: |
BC015969 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
