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    • PTGDS抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW17115
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: PTGDS抗原(重組蛋白)

    英文名稱: PTGDS Antigen (Recombinant Protein)

    別       名: PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS

    儲        存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 23-190 amino acids of human PTGDS

    技術(shù)規(guī)格

    Full name:

    prostaglandin D2 synthase 21kDa (brain)

    Synonyms:

    PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS

    Swissprot:

    P41222

    Gene Accession:

    BC005939

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

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