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    • POU5F1抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW17066
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: POU5F1抗原(重組蛋白)

    英文名稱: POU5F1 Antigen (Recombinant Protein)

    別      名: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

    儲      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 1-150 amino acids of human POU5F1

    技術(shù)規(guī)格

    Full name:

    POU class 5 homeobox 1

    Synonyms:

    OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

    Swissprot:

    Q01860

    Gene Accession:

    BC117435

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

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