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      • 目錄號 : TW16889
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      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: MVP抗原(重組蛋白)

    英文名稱: MVP Antigen (Recombinant Protein)

    別      名: LRP, VAULT1

    儲      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a C terminal 300 amino acids of human MVP

    技術(shù)規(guī)格

    Full name:

    major vault protein

    Synonyms:

    LRP, VAULT1

    Swissprot:

    Q14764

    Gene Accession:

    BC015623

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

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