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    • OCLN抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW16973
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: OCLN抗原(重組蛋白)

    英文名稱: OCLN Antigen (Recombinant Protein)

    別      名: BLCPMG

    儲      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 266-522 amino acids of human OCLN

    技術(shù)規(guī)格

    Full name:

    Occludin

    Synonyms:

    BLCPMG

    Swissprot:

    Q16625

    Gene Accession:

    BC029886

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

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