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    • MUTYH抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW16887
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: MUTYH抗原(重組蛋白)

    英文名稱: MUTYH Antigen (Recombinant Protein)

    別      名: MYH

    儲      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a C terminal 300 amino acids of human MUTYH

    技術(shù)規(guī)格

    Full name:

    mutY DNA glycosylase

    Synonyms:

    MYH

    Swissprot:

    Q9UIF7

    Gene Accession:

    BC003178

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

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