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    • CDH3抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW16408
      • 應(yīng)用 : 僅限于科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: CDH3抗原(重組蛋白)

    英文名稱: CDH3 Antigen (Recombinant Protein)

    別      名: CDHP; HJMD; PCAD

    儲      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to C terminal 250 amino acids of human CDH3

    技術(shù)規(guī)格

    Full name:

    Cadherin 3, type 1, P-cadherin (placental)

    Synonyms:

    CDHP; HJMD; PCAD

    Swissprot:

    P22223

    Gene Accession:

    BC014462

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

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