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    • GM2A抗原(重組蛋白)

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      價(jià)格:
      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW11238
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱:GM2A 抗原(重組蛋白)

    英文名稱:GM2A Antigen (Recombinant Protein)

    別      名:GM2 ganglioside activator; SAP-3; GM2-AP

    相關(guān)類別:抗原

    儲(chǔ)      存:冷凍(-20℃)

    概述

    Fusion protein corresponding to a region derived from 34-193 amino acids of human GM2A


    技術(shù)規(guī)格

    Full name:

    GM2 ganglioside activator

    Synonyms:

    SAP-3; GM2-AP

    Swissprot:

    P17900

    Gene Accession:

    BC009273

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.


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