購(gòu)物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
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Background: |
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. |
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Applications: |
WB, IHC |
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Name of antibody: |
ITGB4(Phospho-Tyr1510) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine1510(R-D-Y(p)-S-T) derived from Human ITGB4 . |
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Full name: |
integrin, beta 4 |
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Synonyms： |
CD104 |
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SwissProt: |
P16144 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
202 kDa |
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WB Positive control: |
HepG2 cells lysates treated with Na2VO3 |
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WB Recommended dilution: |
500-1000 |
