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中文名稱：CDK7抗原（重組蛋白）
英文名稱： CDK7 Antigen (Recombinant Protein)
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 12-295 amino acids of human CDK7 |
技術(shù)規(guī)格
Full name:
cyclin-dependent kinase 7
Synonyms:
CAK1, HCAK, MO15, STK1, CDKN7, p39MO15
Swissprot:
P50613
Gene Accession:
BC000834
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
