購物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
Background:
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Applications:
ELISA, WB, IHC
Name of antibody:
ITGA2B
Immunogen:
Fusion protein of human ITGA2B
Full name:
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyms：
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16
SwissProt:
P08514
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human colon cancer and human lung cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
113 kDa
WB Positive control:
Human fetal liver and placenta tissue
WB Recommended dilution:
200-1000
