購物車
幫助
021-54845833/15800441009
中文名稱：CALD1抗原（重組蛋白）
英文名稱：CALD1 Antigen (Recombinant Protein)
儲(chǔ) 存：冷凍（-20℃）
相關(guān)類別：抗原
概述
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Fusion protein corresponding to a region derived from 26-207 amino acids of human CALD1 |
技術(shù)規(guī)格
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Full name: |
caldesmon 1 |
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Synonyms: |
CDM, HCAD, LCAD, H-CAD, L-CAD, NAG22 |
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Swissprot: |
Q05682 |
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Gene Accession: |
BC040354 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
