購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱：BAK1抗原（重組蛋白）
英文名稱：BAK1 Antigen (Recombinant Protein)
儲(chǔ) 存：冷凍（-20℃）
相關(guān)類別：抗原
概述
|
Fusion protein corresponding to a region derived from 4-187 amino acids of human BAK1 |
技術(shù)規(guī)格
|
Full name: |
BCL2-antagonist/killer 1 |
|
Synonyms: |
BAK; CDN1; BCL2L7; BAK-LIKE |
|
Swissprot: |
Q16611 |
|
Gene Accession: |
BC004431 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
