購物車
幫助
021-54845833/15800441009
中文名稱： 小鼠抗MAP3K7單克隆抗體
技術規(guī)格
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Applications:
WB
Name of antibody:
MAP3K7
Immunogen:
Fusion protein of human MAP3K7
Full name:
mitogen-activated protein kinase kinase kinase 7
Synonyms:
CSCF; FMD2; TAK1; MEKK7; TGF1a
SwissProt:
O43318
WB Predicted band size:
67 kDa
WB Positive control:
K562, Hela, MCF7, COS7, 3T3 and C6 cell lysates
WB Recommended dilution:
1000-5000
