購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Background: |
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
VASP |
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Immunogen: |
Fusion protein of human VASP |
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Full name: |
vasodilator-stimulated phosphoprotein |
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SwissProt: |
P50552 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
40 kDa |
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WB Positive control: |
A549 and HEPG2 cell lysates |
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WB Recommended dilution: |
500-2000 |
