購(gòu)物車(chē)
幫助
021-54845833/15800441009
|
Background: |
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. |
|
Applications: |
WB, IF |
|
Name of antibody: |
SNCA (Phospho-Tyr136) |
|
Immunogen: |
Synthetic peptide of human SNCA (Phospho-Tyr136) |
|
Full name: |
synuclein, alpha (non A4 component of amyloid precursor) (Phospho-Tyr136) |
|
Synonyms： |
PD1; NACP; PARK1; PARK4 |
|
SwissProt: |
P37840 |
|
WB Predicted band size: |
18 kDa |
|
WB Positive control: |
Mouse brain tissue |
|
WB Recommended dilution: |
500-1000 |
|
IF Positive control: |
Hela cells |
|
IF Recommended dilution |
100-200 |
