購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GPSM2 |
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Immunogen: |
Synthetic peptide of human GPSM2 |
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Full name: |
G protein signaling modulator 2 |
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Synonyms: |
LGN; CMCS; PINS; DFNB82 |
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SwissProt: |
P81274 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
30-150 |
