購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗POLH多克隆抗體
英文名稱： Anti-POLH rabbit polyclonal antibody
別 名： DNA polymerase eta; XPV; XP-V; RAD30; RAD30A
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： POLH
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
POLH |
|
Immunogen: |
Fusion protein of human POLH |
|
Full name: |
DNA polymerase eta |
|
Synonyms: |
XPV; XP-V; RAD30; RAD30A |
|
SwissProt: |
Q9Y253 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human tonsil and Human thyroid cancer |
|
IHC Recommend dilution: |
50-300 |
|
WB Predicted band size: |
78 kDa |
|
WB Positive control: |
A172, 231, Jurkat, HepG2 and Hela cell lysates |
|
WB Recommended dilution: |
500-2000 |
