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    • 兔抗PBOV1多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW21249
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱 : 兔抗PBOV1多克隆抗體


    英文名稱 : Anti-PBOV1 rabbit polyclonal antibody


    別       名: UC28; UROC28; dJ171N11.2


    相關(guān)類別: 一抗


    儲(chǔ)       存: 冷凍(-20℃)


    宿       主: Rabbit


    抗       原: PBOV1


    反應(yīng)種屬: Human


    標(biāo)  記 物: Unconjugate


    克隆類型: rabbit polyclonal


    技術(shù)規(guī)格

    Background:

    UROC28, also known as PBOV1 (prostate and breast cancer overexpressed 1) or UC28, is a 135 amino acid cytoplasmic and nuclear protein that is expressed in colon, prostate, small intestine, testis and spleen, with lower expression in thymus, ovary and peripheral blood leukocytes. UROC28 is up-regulated in prostate, breast and bladder cancer, and is thereby considered a useful target for diagnosis and treatment of these cancers. UROC28 is encoded by a gene located on human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    PBOV1

    Immunogen:

    Synthetic peptide of human PBOV1

    Full name:

    prostate and breast cancer overexpressed 1

    Synonyms:

    UC28; UROC28; dJ171N11.2

    SwissProt:

    Q9GZY1

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human breast cancer

    IHC Recommend dilution:

    10-50

    WB Predicted band size:

    16 kDa

    WB Positive control:

    Human fetal intestines tissue lysate

    WB Recommended dilution:

    200-1000







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