購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FNIP2 |
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Immunogen: |
Synthetic peptide of human FNIP2 |
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Full name: |
folliculin interacting protein 2 |
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Synonyms: |
FNIPL; MAPO1 |
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SwissProt: |
Q9P278 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
25-100 |
