購物車
幫助
021-54845833/15800441009
|
Background: |
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha. |
|
Applications: |
ELISA, WB |
|
Name of antibody: |
EIF2S1 |
|
Immunogen: |
Synthetic peptide of human EIF2S1 |
|
Full name: |
eukaryotic translation initiation factor 2 subunit alpha |
|
Synonyms: |
EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha |
|
SwissProt: |
P05198 |
|
ELISA Recommended dilution: |
5000-10000 |
|
WB Predicted band size: |
36 kDa |
|
WB Positive control: |
NIH/3T3 and A172 cell lysates |
|
WB Recommended dilution: |
200-1000 |
