購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗MCM10多克隆抗體
英文名稱(chēng)： Anti-MCM10 rabbit polyclonal antibody
別 名： CNA43; DNA43; PRO2249
儲(chǔ) 存： 冷凍（-20℃）
抗 原： MCM10
宿 主： Rabbit
相關(guān)類(lèi)別： 一抗
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MCM10 |
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Immunogen: |
Fusion protein of human MCM10 |
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Full name: |
minichromosome maintenance 10 replication initiation factor |
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Synonyms: |
CNA43; DNA43; PRO2249 |
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SwissProt: |
Q7L590 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
30-150 |
