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    • PDCD1抗原

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      • 品牌 : 通蔚生物
      • 目錄號 : TW18001
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ug
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    中文名稱: PDCD1抗原 

    英文名稱: PDCD1 Antigen

    相關(guān)類別: 抗原

    儲    存 冷凍(-20℃) 

    概述

    Synthetic peptide corresponding to a region derived from 270-284 amino acids of human Programmed cell death 1

    技術(shù)規(guī)格

    Full name

    Programmed cell death 1

    Synonyms

    PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l

    Swissprot

    Q15116

    Gene Accession

    NP_005009

    Background

    This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

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