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    • OPTN抗原(重組蛋白)

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      價(jià)格:
      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW17906
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ug
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    中文名稱: OPTN抗原(重組蛋白)

    英文名稱: OPTN Antigen (Recombinant Protein)

    別      名: optineurin; NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

    儲(chǔ)       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to C terminal 166 amino acids of human OPTN

    技術(shù)規(guī)格

    Full name:

    optineurin

    Synonyms:

    NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

    Swissprot:

    Q96CV9

    Gene Accession:

    BC013876

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

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