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    • PAK6抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW16995
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: PAK6抗原(重組蛋白)

    英文名稱: PAK6 Antigen (Recombinant Protein)

    別      名: PAK5

    儲(chǔ)      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 407-658 amino acids of human PAK6

    技術(shù)規(guī)格

    Full name:

    p21 protein (Cdc42/Rac)-activated kinase 6

    Synonyms:

    PAK5

    Swissprot:

    Q9NQU5

    Gene Accession:

    BC035596

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

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