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中文名稱： CAST抗原（重組蛋白）
英文名稱： CAST Antigen (Recombinant Protein)
別 名： BS-17
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human CAST |
技術規(guī)格：
|
Full name: |
calpastatin |
|
Synonyms: |
BS-17 |
|
Swissprot: |
P20810 |
|
Gene Accession: |
BC013579 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
