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    • FBXO32抗原(重組蛋白)

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      價(jià)格:
      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW16732
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: FBXO32抗原(重組蛋白)

    英文名稱: FBXO32 Antigen (Recombinant Protein)

    別       名: Fbx32; MAFbx

    儲(chǔ)       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 146-355 amino acids of human FBXO32

    技術(shù)規(guī)格

    Full name:

    F-box protein 32

    Synonyms:

    Fbx32; MAFbx

    Swissprot:

    Q969P5

    Gene Accession:

    BC024030

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

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