購(gòu)物車
幫助
021-54845833/15800441009
克隆類型： mouse monoclonal
|
Background: |
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants. |
|
Applications: |
WB, IHC |
|
Name of antibody: |
SPTAN1 |
|
Immunogen: |
Fusion protein of human SPTAN1 |
|
Full name: |
spectrin alpha, non-erythrocytic 1 |
|
Synonyms: |
NEAS; EIEE5; SPTA2 |
|
SwissProt: |
Q13813 |
|
IHC positive control: |
Human colon tissue and Human liver cancer; Human liver tissue and Human pancreas tissue |
|
IHC Recommend dilution: |
500-2000 |
|
WB Predicted band size: |
285 KD |
|
WB Positive control: |
Hela, Jurkat, SH-SY5Y cell lysates |
|
WB Recommended dilution: |
500-2000 |
