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    • GNAS抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW11260
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱:GNAS抗原(重組蛋白)

    英文名稱:GNAS Antigen (Recombinant Protein)

    儲(chǔ)      存:冷凍(-20℃)

    相關(guān)類別:抗原

    概述

    Fusion protein corresponding to C terminal 200 amino acids of human GNAS


    技術(shù)規(guī)格

    Full name:

    GNAS complex locus

    Synonyms:

    AHO; GSA; GSP; POH; GPSA; NESP; GNAS1; PHP1A; PHP1B; PHP1C; C20orf45

    Swissprot:

    P63092

    Gene Accession:

    NP_000507

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region.


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