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    • DUSP22抗原(重組蛋白)

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      價(jià)格:
      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW10552
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱:DUSP22抗原(重組蛋白)

    英文名稱:DUSP22 Antigen (Recombinant Protein)

    儲(chǔ)       存:冷凍(-20℃)

    相關(guān)類別:抗原

    概述

    Fusion protein corresponding to a region derived from 104-184 amino acids of human DUSP22

    技術(shù)規(guī)格

    Full name:

    dual specificity phosphatase 22

    Synonyms:

    VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2

    Swissprot:

    Q9NRW4

    Gene Accession:

    BC016844

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.


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